99% Chlormadinone Acetate powder E-mail: email@example.com
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(1) Chloromartanone acetate (CMA) is a derivative of progesterone
(17-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione), first synthesized
in 1961, Used as an effective oral hormone for progesterone
Alternative therapy (HRT), and contraceptive with ethinyl estradiol
(2) Chloroformone acetate has a strong progestogen effect, about
one third higher than progesterone, and can be based on the role of
estrogen before the change, that estrogen can promote the formation
of progesterone receptors and uterus Endometrial proliferation.
Like progesterone, it is anti-estrogen and does not have some
androgen effects (for contraceptive and HRT doses).
(3) contrary to progesterone, it has a slight role in
glucocorticoids, and obvious anti-androgen effects, no salt
corticosteroid effect. There is no evidence that CMA is not
pregnant in humans.
(4) It is speculated that the anti-androgenic effect of CMA is the
result of competitive inhibition of endogenous testosterone and
dihydrotestosterone and competitive inhibition of 5-reductase in
combination with androgen receptors. In this respect, the dose of
CMA is critical; agonism is observed when the dose is increased
from the optimal dose for antagonism.
(5) Glucoside acetate is a strong anti-gonadotropin effect through
negative feedback on the secretion of gonadotropin. More than 20
years of contraceptive use has been used in only patients with
arterial risk. The clinical and metabolic tolerances of CMA have
been demonstrated in many clinical studies for a duration of up to
(6) The latest application of CMA as an oral contraceptive in
combination with EE (Neo Eunomin, Belara) has proven to be very
successful, and the study reported excellent contraceptive
efficacy, high tolerance and compliance, due to good side effects
And the positive effects of pre-existing dysmenorrhea, skin and
Chloramphenic acid hydrochloride is clinically used as a hormone
contraceptive, in part because it reduces estrogen levels, and in
order to improve the effectiveness of contraceptive methods,
clomethanone is usually used in combination with ethinyl estradiol
for this purpose. It is chloramphenicol acetate.
Chloromartanone acetate (CMA) is a naturally occurring progesterone
derivative that exhibits high affinity and activity in progesterone
It has an antiestrogen effect, contrary to natural progesterone,
with moderate antiandrogenic properties. CMA acts by blocking the
androgen receptors in the target organ and by reducing the activity
of the skin 5? -reductase.
It inhibits gonadotropin secretion, thereby reducing ovarian and
adrenal androgen production. CMA inhibits ovulation due to
inhibition or destruction of endogenous gonadotropin secretion,
showing high contraceptive efficacy, thereby inhibiting follicular
growth and maturation. In addition, it inhibits endometrial
thickness and increases the viscosity of cervical mucus.
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