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Chlormadinone acetate

Country/Region china
Company Shenzhen Sendi Biotechnology Co.,Ltd
Categories Low Molecular Weight Chondroitin Sulfate
Telephone +86-755-66601416
ICP License Issued by the Chinese Ministry
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    Chlormadinone acetate

    99% Chlormadinone Acetate powder E-mail: claire@chembj.com Skype: live:695059711 whats app: +8615527046746 Quick Detail Description(1) Chloromartanone acetate (CMA) is a derivative of progesterone (17-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione), first synthesized in 1961, Used as an...

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    99% Chlormadinone Acetate powder E-mail: claire@chembj.com

    Skype: live:695059711 whats app: +8615527046746


    Quick Detail

    Product Name

    Chlormadinone acetate

    Chemical Name

    Addyi

    CAS Number

    302-22-7

    EINECS Number

    206-118-0

    Molecular Formula

    C23H29ClO4

    Molecular Weight

    294.17

    Molecular Structure


    Melting Point

    139-143℃

    Assay

    99.5%

    Appearance

    White powder

    Description :
    (1) Chloromartanone acetate (CMA) is a derivative of progesterone (17-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione), first synthesized in 1961, Used as an effective oral hormone for progesterone

    Alternative therapy (HRT), and contraceptive with ethinyl estradiol (EE).

    (2) Chloroformone acetate has a strong progestogen effect, about one third higher than progesterone, and can be based on the role of estrogen before the change, that estrogen can promote the formation of progesterone receptors and uterus Endometrial proliferation. Like progesterone, it is anti-estrogen and does not have some androgen effects (for contraceptive and HRT doses).

    (3) contrary to progesterone, it has a slight role in glucocorticoids, and obvious anti-androgen effects, no salt corticosteroid effect. There is no evidence that CMA is not pregnant in humans.

    (4) It is speculated that the anti-androgenic effect of CMA is the result of competitive inhibition of endogenous testosterone and dihydrotestosterone and competitive inhibition of 5-reductase in combination with androgen receptors. In this respect, the dose of CMA is critical; agonism is observed when the dose is increased from the optimal dose for antagonism.

    (5) Glucoside acetate is a strong anti-gonadotropin effect through negative feedback on the secretion of gonadotropin. More than 20 years of contraceptive use has been used in only patients with arterial risk. The clinical and metabolic tolerances of CMA have been demonstrated in many clinical studies for a duration of up to 2.5 years.

    (6) The latest application of CMA as an oral contraceptive in combination with EE (Neo Eunomin, Belara) has proven to be very successful, and the study reported excellent contraceptive efficacy, high tolerance and compliance, due to good side effects And the positive effects of pre-existing dysmenorrhea, skin and hair condition.

    Applications

    Chloramphenic acid hydrochloride is clinically used as a hormone contraceptive, in part because it reduces estrogen levels, and in order to improve the effectiveness of contraceptive methods, clomethanone is usually used in combination with ethinyl estradiol for this purpose. It is chloramphenicol acetate.

    Chloromartanone acetate (CMA) is a naturally occurring progesterone derivative that exhibits high affinity and activity in progesterone receptors.

    It has an antiestrogen effect, contrary to natural progesterone, with moderate antiandrogenic properties. CMA acts by blocking the androgen receptors in the target organ and by reducing the activity of the skin 5? -reductase.

    It inhibits gonadotropin secretion, thereby reducing ovarian and adrenal androgen production. CMA inhibits ovulation due to inhibition or destruction of endogenous gonadotropin secretion, showing high contraceptive efficacy, thereby inhibiting follicular growth and maturation. In addition, it inhibits endometrial thickness and increases the viscosity of cervical mucus.

    FAQ

    Q1:Have your product quality been approved by Third Party Lab?

    A:Yes,All products are strictly tested by our QC,confirmed by QA and approved by third party lab in China,USA,Canada,Germany,UK,Italy,France etc.So you will be assured with Good Quality if you choose us.

    Q2:How do you treat quality complaint?

    A:First of all,our QC department will do strict examination of our export products by HPLC,UV,GC,TLC and so on in order to reduce the quality

    Quality Chlormadinone acetate for sale
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